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Prostate CSCs sensitive to gamma-tocotrienol?

Gamma-Tocotrienol Kills Prostate Cancer Stem Cells, PRNewswire, July 25, 2010. Excerpt: The scientists found that low doses of gamma-tocotrienol cause apoptosis in the prostate cancer stem cells and...

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Researchers Study CSCs as Therapeutic Targets for Mesothelioma

Researchers Study Cancer Stem Cells as Therapeutic Targets for Mesothelioma, Asbestos.com, July 26, 2010. Excerpt: In a study published in the International Journal of Oncology, Cortes-Dericks and...

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Disagreement about melanoma CSCs

The Evolving Science of Cancer Stem Cells by Carmen Phillips, NCI Cancer Bulletin 2010(Jul 27); 7(15). Excerpt: Researchers from Stanford University earlier this month reported in Nature that they had...

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Cell of origin for human prostate cancer

Scientists at UCLA find cell of origin for human prostate cancer by Kim Irwin, UCLA Newsroom, July 29, 2010. Excerpts: "Certainly, the dominant thought is that human prostate cancer arose from the...

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Oxygen, hypoxia and the stem cell niche

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche by Ahmed Mohyeldin, Tomás Garzón-Muvdi and Alfredo Quiñones-Hinojosa, Cell Stem Cell 2010(Aug 6); 7(2): 150-61. Review. [PubMed...

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Partnership Pays Off

Northern Exposure by Emmet Pierce, San Diego Business Journal, August 16, 2010. Excerpt: An example of San Diegans collaborating with Canadians is the work that has taken place at the UC San Diego...

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Putative tumor-initiating progenitor cells predict poor lung cancer prognosis

Adult lung stem cells, vital to injury repair, associated with poor cancer prognosis, News release, UCLA Newsroom, August 17, 2010. Excerpts: Adult stem cells that are vital for airway repair in the...

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Therapeutic implications of colon CSCs

Therapeutic implications of colon cancer stem cells by Eros Fabrizi and 3 co-authors, including Lucia Ricci-Vitiani, World J Gastroenterol 2010(Aug 21); 16(31): 3871-7. OA review. [FriendFeed...

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Selective targeting of neuroblastoma tumour-initiating cells

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens by Kristen M Smith and 16 co-authors, including David R Kaplan, EMBO Mol...

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Two Open Access reviews

1) Cancer Stem Cells in Pancreatic Cancer by Qi Bao and 6 co-authors, including Karl-Walter Jauch and Christiane J Bruns, Cancers 2010(Aug 19); 2(3): 1629-41. [Full text PDF][Scribd entry][Part of the...

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Isolation and killing of candidate CML stem cells by antibody targeting

Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein by Marcus Järås and 10 co-authors, including Thoas Fioretos, Proc Natl...

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Some breast cancer tumors may not originate from stem cells?

Surprise breast cancer source by Jennifer Welsh,TheScientist.com, September 2, 2010. First paragraph: Some breast cancer tumors may not originate from stem cells as previously believed, according to a...

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On the low frequency of tumor-initiating cells

Tumor-Initiating Cells Are Rare in Many Human Tumors by Kota Ishizawa and 16 co-authors, including Benjamin G Neel and William Matsui, Cell Stem Cell 2010(Sep 3); 7(3): 279-282. [FriendFeed...

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Must the last CML cell be killed?

Do we have to kill the last CML cell? DM Ross, TP Hughes and JV Melo, Leukemia 2010(Sep 16) [Epub ahead of print][FriendFeed entry][PubMed citation][Full text]. The abstract of this OA review:Previous...

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Critical molecular pathways in CSCs of CML

Critical molecular pathways in cancer stem cells of chronic myeloid leukemia by Y Chen, C Peng, C Sullivan, D Li and S Li, Leukemia 2010(Sep); 24(9): 1545-54. Epub 2010 Jun 24. [Connotea...

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Insights into the stem cells of CML

Insights into the stem cells of chronic myeloid leukemia by I Sloma, X Jiang, A C Eaves and C J Eaves, Leukemia 2010(Sep 23). [Epub ahead of print][PubMed citation]. Abstract: Chronic myeloid leukemia...

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OA Video Protocol from Matsui Lab

Isolation of Stem Cells from Human Pancreatic Cancer Xenografts by Zeshaan Rasheed, Qiuju Wang, William Matsui, J Vis Exp 2010(Sep 26);(43). pii: 2169. OA Video Protocol.

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Trials to target CSCs

U-M stem cell trial shows promise against breast cancer by Kim Kozlowski, The Detroit News, September 30, 2010. Excerpt: The research will be highlighted next week in Detroit during the World Stem Cell...

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From the Editor

I'll be taking some time away from blogging for the remainder of 2010. My tentative plan is to return with a different approach. For example, it may rely much less on blog posts, and more on short news...

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Two new initiatives from the CSCC

The Cancer Stem Cell Consortium (CSCC) has announced the launch of two new initiatives for 2011-2012. Information about these initiatives is available via the websites of the CSCC and Genome Canada.The...

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